In a cyclical way, Anguissola has finished her life's work the same way she began it - with a self-portrait. The artist shows herself majestically seated on a red velvet tasselled chair, which contrasts with the usual sombre, dark clothing that she can be seen wearing throughout most of her self-portraits. In earlier portraits she paints herself at an easel with brushes and palettes in hand, playing a musical instrument, or holding the emblems of her noble family - attributes that she promoted as a prospective young courtier. Here she shows herself as a woman of letters. In her right hand she is holding a letter, while she holds a book in her left hand, marking her place with her index finger between the pages. Anguissola's lined face and deeply hooded eyes suggest that she recognizes that this painting might be her last as she maintains eye contact with the viewer. She understood the power of art to survive through time, and uses it here to commemorate her own life and reputation.
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